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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
Q9UN86
USC-OGP 2-DE database
:
Q9UN86
Q9UN86
General information about the entry
View entry in simple text format
Entry name
G3BP2_HUMAN
Primary accession number
Q9UN86
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Ras GTPase-activating protein-binding protein 2; Short=G3BP-2; AltName: Full=GAP SH3 domain-binding protein 2;.
Gene name
Name=G3BP2
Synonyms=KIAA0660
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1133
:
pI=5.37; Mw=64830
Cross-references
UniProtKB/Swiss-Prot
Q9UN86; G3BP2_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
G3BP2_HUMAN
Primary accession number
Q9UN86
Secondary accession number(s)
A8K6X1 O60606 O75149 Q9UPA1
Sequence was last modified on
October 17, 2006 (version 2)
Annotations were last modified on
March 15, 2017 (version 165)
Name and origin of the protein
Description
RecName: Full=Ras GTPase-activating protein-binding protein 2; Short=G3BP-2; AltName: Full=GAP SH3 domain-binding protein 2;
Gene name
Name=G3BP2
Synonyms=KIAA0660
Encoded on
Name=G3BP2; Synonyms=KIAA0660
Keywords
3D-structure
;
Alternative splicing
;
Complete proteome
;
Cytoplasm
;
Direct protein sequencing
;
Isopeptide bond
;
Methylation
;
mRNA transport
;
Phosphoprotein
;
Polymorphism
;
Reference proteome
;
RNA-binding
;
Transport
;
Ubl conjugation
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
AF145284; AAD51932.1
; -; mRNA
EMBL
AB014560; BAA31635.2
; ALT_INIT; mRNA
EMBL
AF051311; AAC15705.1
; -; mRNA
EMBL
AF053535; AAC95292.1
; -; mRNA
EMBL
AK291786; BAF84475.1
; -; mRNA
EMBL
CH471057; EAX05742.1
; -; Genomic_DNA
EMBL
BC011731; AAH11731.1
; -; mRNA
CCDS
CCDS3571.1; -. [Q9UN86-1]
; .
CCDS
CCDS3572.1; -. [Q9UN86-2]
; .
RefSeq
NP_036429.2; NM_012297.4. [Q9UN86-1]
; .
RefSeq
NP_987100.1; NM_203504.2. [Q9UN86-2]
; .
RefSeq
NP_987101.1; NM_203505.2. [Q9UN86-1]
; .
RefSeq
XP_005263439.1; XM_005263382.2. [Q9UN86-1]
; .
RefSeq
XP_005263440.1; XM_005263383.3. [Q9UN86-1]
; .
RefSeq
XP_011530743.1; XM_011532441.2. [Q9UN86-1]
; .
RefSeq
XP_016864365.1; XM_017008876.1. [Q9UN86-1]
; .
RefSeq
XP_016864366.1; XM_017008877.1. [Q9UN86-1]
; .
RefSeq
XP_016864367.1; XM_017008878.1. [Q9UN86-2]
; .
RefSeq
XP_016864368.1; XM_017008879.1. [Q9UN86-2]
; .
UniGene
Hs.303676; -
; .
UniGene
Hs.613996; -
; .
PDB
5DRV; X-ray
; 2.75 A; A=1-139
PDBsum
5DRV; -
; .
ProteinModelPortal
Q9UN86; -
; .
SMR
Q9UN86; -
; .
BioGrid
115237; 64
; .
DIP
DIP-50299N; -
; .
IntAct
Q9UN86; 33
; .
MINT
MINT-3082700; -
; .
STRING
9606.ENSP00000352738; -
; .
iPTMnet
Q9UN86; -
; .
PhosphoSitePlus
Q9UN86; -
; .
BioMuta
G3BP2; -
; .
DMDM
116242482; -
; .
EPD
Q9UN86; -
; .
PaxDb
Q9UN86; -
; .
PeptideAtlas
Q9UN86; -
; .
PRIDE
Q9UN86; -
; .
Ensembl
ENST00000357854; ENSP00000350518
; ENSG00000138757. [Q9UN86-2]; .
Ensembl
ENST00000359707; ENSP00000352738
; ENSG00000138757. [Q9UN86-1]; .
Ensembl
ENST00000395719; ENSP00000379069
; ENSG00000138757. [Q9UN86-1]; .
GeneID
9908; -
; .
KEGG
hsa:9908; -
; .
UCSC
uc003hir.4; human. [Q9UN86-1]
; .
CTD
9908; -
; .
DisGeNET
9908; -
; .
GeneCards
G3BP2; -
; .
HGNC
HGNC:30291; G3BP2
; .
HPA
HPA018304; -
; .
HPA
HPA018425; -
; .
neXtProt
NX_Q9UN86; -
; .
OpenTargets
ENSG00000138757; -
; .
PharmGKB
PA162389134; -
; .
eggNOG
KOG0116; Eukaryota
; .
eggNOG
ENOG410YV57; LUCA
; .
GeneTree
ENSGT00390000011365; -
; .
HOGENOM
HOG000220838; -
; .
HOVERGEN
HBG007211; -
; .
InParanoid
Q9UN86; -
; .
OMA
MEQNESD; -
; .
OrthoDB
EOG091G0GAN; -
; .
PhylomeDB
Q9UN86; -
; .
TreeFam
TF325464; -
; .
GeneWiki
G3BP2; -
; .
GenomeRNAi
9908; -
; .
PRO
PR:Q9UN86; -
; .
Proteomes
UP000005640; Chromosome 4
; .
Bgee
ENSG00000138757; -
; .
CleanEx
HS_G3BP2; -
; .
ExpressionAtlas
Q9UN86; baseline and differential
; .
Genevisible
Q9UN86; HS
; .
GO
GO:0005737; C:cytoplasm
; NAS:UniProtKB; .
GO
GO:0005829; C:cytosol
; IDA:HPA; .
GO
GO:0030529; C:intracellular ribonucleoprotein complex
; IBA:GO_Central; .
GO
GO:0003729; F:mRNA binding
; IBA:GO_Central; .
GO
GO:0000166; F:nucleotide binding
; IEA:InterPro; .
GO
GO:0030159; F:receptor signaling complex scaffold activity
; NAS:UniProtKB; .
GO
GO:0003723; F:RNA binding
; IDA:UniProtKB; .
GO
GO:0007253; P:cytoplasmic sequestering of NF-kappaB
; NAS:UniProtKB; .
GO
GO:0051028; P:mRNA transport
; IEA:UniProtKB-KW; .
GO
GO:0007265; P:Ras protein signal transduction
; NAS:UniProtKB; .
CDD
cd00780; NTF2
; 1; .
Gene3D
3.10.450.50; -
; 1; .
Gene3D
3.30.70.330; -
; 1; .
InterPro
IPR002075; NTF2
; .
InterPro
IPR032710; NTF2-like_dom
; .
InterPro
IPR018222; Nuclear_transport_factor_2_euk
; .
InterPro
IPR012677; Nucleotide-bd_a/b_plait
; .
InterPro
IPR000504; RRM_dom
; .
Pfam
PF02136; NTF2
; 1; .
Pfam
PF00076; RRM_1
; 1; .
SMART
SM00360; RRM
; 1; .
SUPFAM
SSF54427; SSF54427
; 1; .
SUPFAM
SSF54928; SSF54928
; 1; .
PROSITE
PS50177; NTF2_DOMAIN
; 1; .
PROSITE
PS50102; RRM
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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